I assume these are scanned documents. To get the smallest possible scanned files, use Tools>Document Processing>Optimize Scanned PDF (Acrobat XI) or Tools>Optimize>Optimize Scanned Pages (Acrobat DC). Then select to use "Adaptive Compression" with JPEG2000 or JBIG2 compression.
That should bring your file size down quite a bit.
Karl Heinz Kremer
PDF Acrobatics Without a Net
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